Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809640 | 1.00 | CYSLTR1 (0.46) | CYSLTR1GPBAR1CYSLTR2ALOX5FFAR1 | |
| SCHEMBL7810479 | 0.89 | ALOX5AP (0.41) | CYSLTR1GPBAR1ALOX5ALOX5AP | |
| SCHEMBL7810478 | 0.89 | ALOX5AP (0.41) | CYSLTR1GPBAR1ALOX5ALOX5AP | |
| SCHEMBL7810468 | 0.85 | PDE10A (0.48) | CYSLTR1GPBAR1CYSLTR2ALOX5ALOX5AP | |
| SCHEMBL7810465 | 0.85 | PDE10A (0.48) | CYSLTR1GPBAR1CYSLTR2ALOX5ALOX5AP | |
| SCHEMBL7801525 | 0.80 | MAPT (0.56) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL7801585 | 0.80 | CYSLTR1 (0.49) | CYSLTR1GPBAR1CYSLTR2ALOX5FFAR1 | |
| SCHEMBL7801584 | 0.80 | CYSLTR1 (0.49) | CYSLTR1GPBAR1CYSLTR2ALOX5FFAR1 | |
| SCHEMBL7813341 | 0.77 | LTB4R (0.48) | CYSLTR1GPBAR1CYSLTR2ALOX5FFAR1 | |
| SCHEMBL7806683 | 0.77 | CYSLTR1 (0.48) | CYSLTR1GPBAR1ALOX5ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685478-B1 | QUINOLINE DERIVATIVES | UBE INDUSTRIES (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5591752-A | LEUKOTRIENE ANTAGONIST, ANTIALLERGEN, ANTIINFLAMMATORY AGENT, DIBENZ(B,E)OXEPINE | UBE INDUSTRIES, LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0685478-A1 | QUINOLINE DERIVATIVE | UBE INDUSTRIES, LTD. (JP) | 1995-12-06 | — | — | EP | disclosed |