SCHEMBL7809649

SCHEMBL7809649

OC(CCc1ccccc1)c1ccccc1C(O)CCc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 10/20 0.54
CYP2C19 P33261 1/20 0.47
TDP1 Q9NUW8 1/20 0.46
ANPEP P15144 2/20 0.46
ERAP1 Q9NZ08 2/20 0.46
ERAP2 Q6P179 1/20 0.46
IDO1 P14902 1/20 0.44
TDO2 P48775 1/20 0.44
ACP3 P15309 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27465775 0.90 ABCB1 (0.55) ABCB1CYP2C19
SCHEMBL1837302 0.88 POLB (0.50) ABCB1CYP2C19
SCHEMBL9657320 0.86 ABCB1 (0.48) ABCB1CYP2C19
SCHEMBL30849674 0.86 IDO1 (0.58) ABCB1CYP2C19IDO1TDO2
SCHEMBL30849672 0.86 ABCB1 (0.48) ABCB1CYP2C19
SCHEMBL3913665 0.83 ABCB1 (0.59) ABCB1
SCHEMBL2987540 0.83 ABCB1 (0.43) ABCB1CYP2C19
SCHEMBL16721027 0.83 METAP2 (0.52) ABCB1CYP2C19ACP3
SCHEMBL30849681 0.83 ABCB1 (0.59) ABCB1
SCHEMBL936318 0.82 PPARG (0.50) CYP2C19TDP1ANPEPERAP1ERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6316170-B2 COATING, EXPOSURE, DEVELOPMENT AND HEAT TREATMENT KABUSHIKI KAISHA TOSHIBA (JP) 2001-11-13 US disclosed
US-20010006767-A1 Developing solution and method of forming polyimide pattern by using the developing solution YOSHIAKI KAWAMONZEN 2001-07-05 US disclosed
EP-0485472-A1 BIS-CYCLIC PHOSPHITE COMPOUNDS AND POLYMERIC MATERIALS STABILIZED THEREWITH EASTMAN KODAK COMPANY (US) 1992-05-20 EP disclosed
EP-0437493-A1 CYCLIC PHOSPHITES AND STABILIZED POLYMERIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1991-07-24 EP disclosed
WO-1991001987-A1 BIS-CYCLIC PHOSPHITE COMPOUNDS AND POLYMERIC MATERIALS STABILIZED THEREWITH EASTMAN KODAK COMPANY (US) 1991-02-21 WO disclosed
EP-0412028-A1 Bis-cyclic phosphite compounds and polymeric materials stabilized therewith EASTMAN KODAK COMPANY (US) 1991-02-06 EP disclosed
US-4956406-A Oxidation resistance of polypropylene or copolymers also heat resistance and radiation resistance EASTMAN KODAK COMPANY (US) 1990-09-11 US disclosed
US-4929654-A HEAT RESISTANCE, LIGHT RESISTANCE EASTMAN KODAK COMPANY (US) 1990-05-29 US disclosed
WO-1990003976-A1 CYCLIC PHOSPHITES AND STABILIZED POLYMERIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1990-04-19 WO disclosed
EP-0363270-A1 Cyclic phosphites and stabilized polymeric compositions EASTMAN KODAK COMPANY (US) 1990-04-11 EP disclosed