Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAP2 | P11137 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809688 | 0.79 | CAPN1 (0.40) | CAPN1KDM4EMAP2CSF1RALDH1A1 | |
| SCHEMBL7809700 | 0.77 | CAPN1 (0.39) | CAPN1KDM4ECSF1RALDH1A1MAPT | |
| SCHEMBL7816816 | 0.74 | ALDH1A1 (0.40) | CAPN1ALDH1A1TP53RXFP1SMN1; SMN2 | |
| SCHEMBL8692854 | 0.73 | CAPN1 (0.38) | CAPN1 | |
| SCHEMBL7813860 | 0.72 | CAPN1 (0.40) | CAPN1KDM4EALDH1A1POLBNPSR1 | |
| SCHEMBL7810983 | 0.72 | CAPN1 (0.44) | CAPN1ALDH1A1MAPTTP53RXFP1 | |
| SCHEMBL497120 | 0.72 | CAPN1 (0.39) | CAPN1CSF1RMAPTTP53RXFP1 | |
| SCHEMBL7813747 | 0.71 | CAPN1 (0.41) | CAPN1KDM4ECSF1RALDH1A1MAPT | |
| SCHEMBL8691893 | 0.71 | CAPN1 (0.39) | CAPN1KDM4EMAP2CSF1RALDH1A1 | |
| SCHEMBL8691019 | 0.70 | CAPN1 (0.38) | CAPN1CSF1RATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533882-B1 | 2-QUINOLINONE DERIVATIVES, METHODS FOR PREPARING THE SAME AND FUNGICIDES AND INSECTICIDES INCLUDING THEM | KOREA RES INST CHEM TECH (KR) | 2001-02-07 | — | — | EP | disclosed |
| US-5430153-A | Insecticides, fungicides | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-07-04 | — | — | US | disclosed |
| EP-0533882-A1 | 2-QUINOLINONE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-03-31 | — | — | EP | disclosed |
| WO-1992017452-A1 | 2-QUINOLINONE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-10-15 | — | — | WO | disclosed |