SCHEMBL7809784

SCHEMBL7809784

C[Ti](C)([SiH3])(NC(=O)C1CCCCCCCCCCC1)C1C=C(N2CCCC2)c2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.39
P2RX7 Q99572 2/20 0.36
HPGD P15428 2/20 0.35
TSHR P16473 4/20 0.35
ALDH1A1 P00352 4/20 0.34
KDM4E B2RXH2 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HSD17B10 Q99714 1/20 0.33
GAA P10253 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
USP2 O75604 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7952816 0.83 CYP2C19 (0.38) CYP2C19P2RX7HPGDTSHRALDH1A1
SCHEMBL7059143 0.76 DRD2 (0.32) ALDH1A1MAPT
SCHEMBL6442092 0.74 CYP2C19 (0.41) CYP2C19P2RX7HPGDTSHRALDH1A1
SCHEMBL5679095 0.74 CYP2C19 (0.41) CYP2C19P2RX7HPGDTSHRALDH1A1
SCHEMBL6468553 0.73 CYP2C19 (0.40) CYP2C19P2RX7HPGDTSHRALDH1A1
Hydrochloric Acid SCHEMBL7952814 0.72 CYP2C19 (0.39) CYP2C19P2RX7HPGDTSHRALDH1A1
SCHEMBL6471495 0.69 CYP2C19 (0.38) CYP2C19P2RX7HPGDSMN1; SMN2HDAC1
SCHEMBL7949137 0.68 NPC1 (0.36) CYP2C19HPGDTSHRALDH1A1SMN1; SMN2
SCHEMBL6912076 0.65 BCHE (0.38) CYP2C19TSHRALDH1A1MAPTHTT
SCHEMBL7951047 0.65 TSHR (0.32) TSHRALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010027161-A1 Catalyst activators comprising expanded anions THE DOW CHEMICAL COMPANY 2001-10-04 US claimed