Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4541937 | 0.83 | SLC6A4 (0.61) | SLC6A4 | |
| SCHEMBL428829 | 0.81 | SLC6A4 (1.00) | SLC6A4 | |
| SCHEMBL3379399 | 0.81 | SLC6A4 (0.71) | SLC6A4 | |
| Hydrochloric Acid SCHEMBL9772910 | 0.80 | SLC6A4 (0.59) | SLC6A4 | |
| SCHEMBL9772971 | 0.80 | SLC6A4 (0.59) | SLC6A4 | |
| SCHEMBL15292058 | 0.80 | SLC6A4 (0.60) | SLC6A4 | |
| SCHEMBL1275552 | 0.80 | SLC6A4 (0.59) | SLC6A4 | |
| SCHEMBL7201332 | 0.79 | SLC6A4 (0.71) | SLC6A4 | |
| SCHEMBL14161672 | 0.78 | SLC6A4 (0.60) | SLC6A4 | |
| SCHEMBL14207392 | 0.77 | SLC6A4 (0.56) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636623-B1 | Indole derivatives as 5-HT1- like agonists | ASTRAZENECA AB (SE) | 2001-08-16 | — | — | EP | disclosed |
| US-5863935-A | SYNTHESIS OF INDOLE DERIVATIVES OF HETEROCYCLIC COMPOUNDS FOR TREATMENT OF HEADACHES AND MIGRAINES | ZENECA LIMITED (GB) | 1999-01-26 | — | — | US | disclosed |
| US-5466699-A | Indolyl compounds for treating migraine | BURROUGHS WELLCOME CO. (US) | 1995-11-14 | — | — | US | disclosed |
| US-5399574-A | 5-hydroxytryptamine agonists; vasoconstrictors | BURROUGHS WELLCOME CO. (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0636623-A1 | Indole derivatives as 5-HT1- like agonists | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-02-01 | — | — | EP | disclosed |
| EP-0486666-A1 | THERAPEUTIC HETEROCYCLIC COMPOUNDS. | WELLCOME FOUND (GB) | 1992-05-27 | — | — | EP | disclosed |
| WO-1991018897-A1 | THERAPEUTIC HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-12-12 | — | — | WO | disclosed |