SCHEMBL7809939

SCHEMBL7809939

Oc1cccc2c1CC(O)N2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 3/20 0.37
DRD3 P35462 1/20 0.37
CHRNB2 P17787 1/20 0.37
CHRNA4 P43681 1/20 0.37
ALDH1A1 P00352 2/20 0.36
HPGD P15428 2/20 0.36
ALOX15 P16050 2/20 0.36
HSD17B10 Q99714 2/20 0.36
MEN1 O00255 1/20 0.36
APP P05067 1/20 0.36
CYP1A2 P05177 1/20 0.36
GAA P10253 1/20 0.36
CYP2D6 P10635 1/20 0.36
MAPT P10636 1/20 0.36
CYP2C9 P11712 1/20 0.36
TSHR P16473 1/20 0.36
ALOX12 P18054 1/20 0.36
CYP2C19 P33261 1/20 0.36
SNCA P37840 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18689814 0.78 CREBBP (0.39) ALDH1A1MEN1KMT2APARP1CREBBP
SCHEMBL5771626 0.78 CREBBP (0.44) DRD2DRD3CHRNB2CHRNA4MEN1
SCHEMBL28669325 0.74 CHRM3 (0.34) DRD2DRD3CHRNB2CHRNA4ALDH1A1
SCHEMBL28979215 0.69 MEN1 (0.32) ALDH1A1HPGDALOX15HSD17B10MEN1
SCHEMBL2781001 0.68 MAPT (0.55) ALOX15HSD17B10MEN1GAAMAPT
SCHEMBL31517110 0.68 MAPT (0.55) ALOX15HSD17B10MEN1GAAMAPT
SCHEMBL16729472 0.68 DRD2 (0.41) DRD2DRD3CHRM3CHRM2CHRM1
SCHEMBL28323375 0.68 DRD2 (0.41) DRD2DRD3CHRM3CHRM2CHRM1
SCHEMBL28261915 0.67 PARP1 (0.31) ALDH1A1HPGDALOX15HSD17B10MEN1
Bromide SCHEMBL16717336 0.67 DRD2 (0.40) DRD2DRD3CHRM3CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2001226351-A METHOD FOR PRODUCING 4-HYDROXYOXYINDOLE DAISO CO LTD 2001-08-21 JP disclosed