Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 15/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.55 |
| ▸ | F2 | P00734 | 3/20 | 0.50 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7574644 | 0.89 | ESR1 (0.67) | ESR1ESR2PSMB1PSMB5PSMB2 | |
| SCHEMBL7351518 | 0.87 | LTA4H (0.56) | PSMB1PSMB5PSMB2LTA4H | |
| SCHEMBL7442171 | 0.87 | ESR1 (0.59) | ESR1ESR2F2PSMB1PSMB5 | |
| SCHEMBL7820299 | 0.86 | HRH3 (0.57) | PSMB1PSMB5PSMB2LTA4H | |
| SCHEMBL7442357 | 0.84 | F2 (0.70) | ESR1ESR2F2 | |
| SCHEMBL7439386 | 0.82 | F2 (0.67) | ESR1ESR2F2 | |
| SCHEMBL229218 | 0.82 | ESR1 (0.58) | ESR1ESR2PSMB1PSMB5PSMB2 | |
| SCHEMBL7502080 | 0.81 | F2 (0.66) | ESR1ESR2F2LTA4H | |
| SCHEMBL7437099 | 0.80 | F2 (0.68) | ESR1ESR2F2 | |
| SCHEMBL228266 | 0.79 | ESR1 (0.64) | ESR1ESR2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027051-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2001-03-07 | — | — | EP | disclosed |
| EP-1027051-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1998048804-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |