Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179958 | 0.75 | — | — | |
| SCHEMBL18668241 | 0.73 | — | — | |
| SCHEMBL15661027 | 0.69 | — | — | |
| SCHEMBL620354 | 0.69 | — | — | |
| SCHEMBL5806141 | 0.67 | — | — | |
| SCHEMBL9930783 | 0.63 | — | — | |
| Amylene Hydrate SCHEMBL10721 | 0.63 | — | — | |
| SCHEMBL40253 | 0.63 | — | — | |
| Amylene Hydrate SCHEMBL2013421 | 0.63 | ALDH1A1 (0.54) | TSHRTDP1ALDH1A1 | |
| SCHEMBL12819894 | 0.63 | TSHR (0.50) | TSHRTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708767-B1 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR CARBAZOLE AND DIBENZOFURAN DERIVATIVES | ABBOTT LAB (US) | 2001-02-14 | — | — | EP | disclosed |
| EP-0708767-A4 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR CARBAZOLE AND DIBENZOFURAN DERIVATIVES | ABBOTT LAB (US) | 1996-10-02 | — | — | EP | disclosed |
| US-5541333-A | TETHERED HAPTEN INTERMEDIATES | ABBOTT LABORATORIES (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0708767-A1 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR CARBAZOLE AND DIBENZOFURAN DERIVATIVES | ABBOTT LABORATORIES (US) | 1996-05-01 | — | — | EP | disclosed |
| US-5464746-A | Haptens, tracers, immunogens and antibodies for carbazole and dibenzofuran derivatives | ABBOTT LABORATORIES (US) | 1995-11-07 | — | — | US | disclosed |
| WO-1995003296-A1 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR CARBAZOLE AND DIBENZOFURAN DERIVATIVES | ABBOTT LABORATORIES (US) | 1995-02-02 | — | — | WO | disclosed |