SCHEMBL7810380

SCHEMBL7810380

CN(N)C(=S)OCc1ccccc1.NNC(O)=S

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
CA12 O43570 3/20 0.45
CA1 P00915 3/20 0.45
CA2 P00918 3/20 0.45
CA9 Q16790 3/20 0.45
GAA P10253 2/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40
LMNA P02545 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
AOC3 Q16853 1/20 0.38
MAPK1 P28482 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A3 Q01959 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
FABP7 O15540 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8986629 0.78 CA12 (0.52) ALDH1A1CA12CA1CA2CA9
SCHEMBL1158071 0.77 ALDH1A1 (0.52) ALDH1A1CA12CA1CA2CA9
SCHEMBL2240540 0.74 CA12 (0.55) ALDH1A1CA12CA1CA2CA9
SCHEMBL3149010 0.71 ALDH1A1 (0.58) ALDH1A1CA12CA1CA2CA9
SCHEMBL9099866 0.71 ALDH1A1 (0.53) ALDH1A1CA12CA1CA2CA9
SCHEMBL1254822 0.71 ALDH1A1 (0.49) ALDH1A1CA12CA1CA2CA9
SCHEMBL5965380 0.71 ALDH1A1 (0.49) ALDH1A1CA12CA1CA2CA9
Hydrochloric Acid SCHEMBL28276393 0.70 ALDH1A1 (0.56) ALDH1A1CA12CA1CA2CA9
SCHEMBL8986634 0.69
SCHEMBL6317391 0.69 CA12 (0.53) ALDH1A1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0727423-B1 Process for the preparation of sulfonylurea derivatives and intermediates for this process LUCKY LTD (KR) 2001-07-25 EP disclosed
EP-0727424-B1 Process for the preparation of sulfonylurea derivatives LUCKY LTD (KR) 2001-06-20 EP disclosed
EP-0613896-B1 Process for the preparation of sulfonylurea derivatives LUCKY LTD (KR) 1998-07-22 EP disclosed
EP-0727423-A2 Process for the preparation of sulfonylurea derivatives and intermediates for this process LUCKY LTD. (KR) 1996-08-21 EP disclosed
EP-0727424-A2 Process for the preparation of sulfonylurea derivatives and intermediates for this process LUCKY LTD. (KR) 1996-08-21 EP disclosed
US-5534637-A CHEMICAL INTERMEDIATES LUCKY LTD. (KR) 1996-07-09 US disclosed
EP-0602589-B1 Processes for preparation of 5-pyrazolemercaptan derivatives and intermediates thereof LUCKY LTD (KR) 1996-06-26 EP disclosed
US-5468896-A Chemical intermediates for herbicides LUCKY LTD. (KR) 1995-11-21 US disclosed
US-5466854-A From alkyl hydrazine and carbon disulfide LUCKY LTD. (KR) 1995-11-14 US disclosed
US-5416220-A From a dithiocabazate and an ethoxymethylene malonate LUCKY, LTD. (KR) 1995-05-16 US disclosed
US-5405965-A Heating ethylidene dithiocarbazate compound with base LUCKY LTD. (KR) 1995-04-11 US disclosed
EP-0602589-A1 Processes for preparation of 5-pyrazolemercaptan derivatives and intermediates thereof LUCKY LTD. (KR) 1994-06-22 EP disclosed