Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7821139 | 0.71 | KDM4E (0.34) | KDM4E | |
| SCHEMBL7821137 | 0.68 | KDM4E (0.34) | KDM4EALDH1A1TP53GLAGAA | |
| SCHEMBL7822984 | 0.59 | KDM4E (0.38) | KDM4E | |
| SCHEMBL13280215 | 0.56 | KDM4E (0.49) | KDM4EALDH1A1TP53GLAGAA | |
| SCHEMBL24459925 | 0.56 | L3MBTL1 (0.31) | — | |
| SCHEMBL11663652 | 0.55 | MEN1 (0.48) | KDM4EALDH1A1TP53HPGD | |
| SCHEMBL9328654 | 0.54 | MEN1 (0.33) | ALDH1A1TP53HPGD | |
| SCHEMBL8871978 | 0.54 | MEN1 (0.46) | KDM4EALDH1A1TP53HPGD | |
| SCHEMBL11663670 | 0.54 | MEN1 (0.52) | KDM4EALDH1A1TP53HPGD | |
| Chlorothalonil SCHEMBL13279254 | 0.53 | MEN1 (0.56) | ALDH1A1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271392-B1 | Intermediates useful for the synthesis of 1-arylpyrrole pesticides | RHONE-POULENC INC. | 2001-08-07 | — | — | US | claimed |
| EP-0708090-A1 | Intermediates useful for the synthesis of pesticides | RHONE-POULENC AGROCHIMIE (FR) | 1996-04-24 | — | — | EP | claimed |
| US-6271392-B1 | Intermediates useful for the synthesis of 1-arylpyrrole pesticides | RHONE-POULENC INC. | 2001-08-07 | — | — | US | disclosed |
| EP-0708090-A1 | Intermediates useful for the synthesis of pesticides | RHONE-POULENC AGROCHIMIE (FR) | 1996-04-24 | — | — | EP | disclosed |