Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NR2C2 | P49116 | 1/20 | 0.40 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7818169 | 0.99 | GBA1 (0.47) | GBA1KDM4EMAPTMAPK1HPGD | |
| Hydrochloric Acid SCHEMBL7821963 | 0.91 | GBA1 (0.52) | GBA1KDM4EMAPTMAPK1HPGD | |
| SCHEMBL7810637 | 0.84 | MAPT (0.47) | KDM4EMAPTMAPK1HPGDTSHR | |
| Hydrochloric Acid SCHEMBL7821018 | 0.83 | MAPT (0.46) | KDM4EMAPTMAPK1HPGDTSHR | |
| SCHEMBL7820492 | 0.78 | MAPT (0.49) | GBA1KDM4EMAPTMAPK1HPGD | |
| SCHEMBL7821547 | 0.78 | LMNA (0.65) | GBA1KDM4EMAPTMAPK1HPGD | |
| Hydrochloric Acid SCHEMBL7820964 | 0.77 | MAPT (0.48) | GBA1KDM4EMAPTMAPK1HPGD | |
| Hydrochloric Acid SCHEMBL7822581 | 0.77 | LMNA (0.67) | GBA1KDM4EMAPTMAPK1HPGD | |
| SCHEMBL6991703 | 0.76 | CHRM3 (0.44) | HPGDSMN1; SMN2NR2C2TAB1HTT | |
| Hydrochloric Acid SCHEMBL6990940 | 0.75 | CHRM3 (0.43) | HPGDSMN1; SMN2NR2C2TAB1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0677049-B1 | QUINAZOLINE DERIVATIVES | YUHAN CORP LTD (KR) | 2001-07-25 | — | — | EP | claimed |
| EP-0677049-A1 | QUINAZOLINE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1995-10-18 | — | — | EP | claimed |
| WO-1994014795-A1 | QUINAZOLINE DERIVATIVES | YUHAN CORPORATION (KR) | 1994-07-07 | — | — | WO | claimed |
| EP-0677049-B1 | QUINAZOLINE DERIVATIVES | YUHAN CORP LTD (KR) | 2001-07-25 | — | — | EP | disclosed |
| CN-1058265-C | Quinazoline derivatives | YUHAN CORP (KR) | 2000-11-08 | — | — | CN | disclosed |
| US-5686458-A | Quinazoline deriviates for treating peptic ulcer | YUHAN CORPORATION (KR) | 1997-11-11 | — | — | US | disclosed |
| EP-0677049-A1 | QUINAZOLINE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1995-10-18 | — | — | EP | disclosed |
| WO-1994014795-A1 | QUINAZOLINE DERIVATIVES | YUHAN CORPORATION (KR) | 1994-07-07 | — | — | WO | disclosed |