Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 19/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1139295 | 1.00 | CTSS (0.50) | CTSS | |
| SCHEMBL1139344 | 1.00 | CTSS (0.50) | CTSS | |
| SCHEMBL1139312 | 0.93 | CTSS (0.49) | CTSS | |
| SCHEMBL1139665 | 0.93 | CTSS (0.49) | CTSS | |
| SCHEMBL12855879 | 0.92 | CTSS (0.51) | CTSS | |
| SCHEMBL1139432 | 0.92 | CTSS (0.52) | CTSS | |
| SCHEMBL1139887 | 0.92 | CTSS (0.51) | CTSS | |
| SCHEMBL1140013 | 0.92 | CTSS (0.51) | CTSS | |
| SCHEMBL1139362 | 0.92 | CTSS (0.52) | CTSS | |
| SCHEMBL1139124 | 0.91 | CTSS (0.49) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440521-B1 | NOVEL CYCLOPENTANE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2014-04-30 | — | — | EP | disclosed |
| WO-2010142650-A1 | NOVEL CYCLOPENTANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-12-16 | — | — | WO | disclosed |