Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.57 |
| ▸ | CTSL | P07711 | 15/20 | 0.57 |
| ▸ | CTSK | P43235 | 2/20 | 0.57 |
| ▸ | CTSB | P07858 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1139096 | 1.00 | CTSS (0.57) | CTSSCTSLCTSKCTSB | |
| SCHEMBL1139217 | 1.00 | CTSS (0.57) | CTSSCTSLCTSKCTSB | |
| SCHEMBL7808031 | 0.91 | CTSS (0.52) | CTSSCTSLCTSKCTSB | |
| SCHEMBL1139017 | 0.91 | CTSS (0.52) | CTSSCTSLCTSKCTSB | |
| SCHEMBL1139505 | 0.91 | CTSS (0.52) | CTSSCTSLCTSKCTSB | |
| SCHEMBL1139860 | 0.91 | CTSS (0.50) | CTSSCTSLCTSKCTSB | |
| SCHEMBL1139074 | 0.91 | CTSS (0.50) | CTSSCTSLCTSKCTSB | |
| SCHEMBL15678490 | 0.90 | CTSS (0.49) | CTSSCTSLCTSKCTSB | |
| SCHEMBL1139623 | 0.89 | CTSS (0.57) | CTSSCTSLCTSKCTSB | |
| SCHEMBL1139515 | 0.89 | CTSS (0.57) | CTSSCTSLCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142650-A1 | NOVEL CYCLOPENTANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-12-16 | — | — | WO | disclosed |