⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7818558 | 1.00 | — | — | |
| SCHEMBL7818551 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL9438420 | 0.98 | CHRM2 (0.56) | — | |
| SCHEMBL7811397 | 0.86 | CHRM1 (0.42) | — | |
| SCHEMBL231364 | 0.86 | CHRM1 (0.42) | — | |
| SCHEMBL231365 | 0.86 | CHRM1 (0.42) | — | |
| Hydrochloric Acid SCHEMBL6169933 | 0.84 | ALDH1A1 (0.43) | — | |
| Hydrochloric Acid SCHEMBL7701666 | 0.84 | ALDH1A1 (0.43) | — | |
| SCHEMBL14033267 | 0.79 | CHRM1 (0.39) | — | |
| Carbamic Acid SCHEMBL7831823 | 0.76 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764165-B1 | PREPARATION OF STEREOCHEMICALLY PURE OXIMES WITH MUSCARINIC ACTIVITY | WARNER LAMBERT CO (US) | 2001-11-07 | — | — | EP | disclosed |
| EP-0764165-A1 | PREPARATION OF STEREOCHEMICALLY PURE OXIMES WITH MUSCARINIC ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1997-03-26 | — | — | EP | disclosed |
| EP-0445731-B1 | Azabicyclo and azacyclo oxime and amine cholinergic agents and pharmaceutically acceptable salts thereof | WARNER LAMBERT CO (US) | 1996-01-10 | — | — | EP | disclosed |
| WO-1995034562-A1 | PREPARATION OF STEREOCHEMICALLY PURE OXIMES WITH MUSCARINIC ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1995-12-21 | — | — | WO | disclosed |
| US-5346911-A | Analgesics, cognition activators, treatment of alzheimer*s s disease | WARNER-LAMBERT COMPANY (US) | 1994-09-13 | — | — | US | disclosed |
| EP-0445731-A1 | Azabicyclo and azacyclo oxime and amine cholinergic agents and pharmaceutically acceptable salts thereof | WARNER-LAMBERT COMPANY (US) | 1991-09-11 | — | — | EP | disclosed |