Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 18/20 | 0.55 |
| ▸ | EDNRA | P25101 | 18/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9459403 | 0.88 | EDNRB (0.53) | EDNRBEDNRA | |
| SCHEMBL9367683 | 0.86 | EDNRB (0.66) | EDNRBEDNRA | |
| SCHEMBL9372708 | 0.84 | EDNRB (0.64) | EDNRBEDNRA | |
| SCHEMBL9059035 | 0.84 | EDNRB (0.50) | EDNRBEDNRACYP1A2 | |
| SCHEMBL9372696 | 0.83 | EDNRB (0.52) | EDNRBEDNRA | |
| SCHEMBL9371781 | 0.83 | EDNRB (0.51) | EDNRBEDNRA | |
| SCHEMBL6781616 | 0.82 | EDNRB (0.65) | EDNRBEDNRA | |
| SCHEMBL8703985 | 0.80 | EDNRB (0.62) | EDNRBEDNRA | |
| SCHEMBL7808396 | 0.79 | EDNRB (0.45) | EDNRBEDNRACYP1A2 | |
| SCHEMBL12095218 | 0.79 | EDNRB (0.45) | EDNRBEDNRACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802193-B1 | Process for the preparation of substituted pyrimidines | LONZA AG (CH) | 2001-10-17 | — | — | EP | disclosed |
| US-5840892-A | Process for the preparation of substituted pyrimidines | LONZA AG (CH) | 1998-11-24 | — | — | US | disclosed |
| EP-0802193-A1 | Process for the preparation of substituted pyrimidines | LONZA AG (CH) | 1997-10-22 | — | — | EP | disclosed |