Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 20/20 | 0.65 |
| ▸ | EDNRA | P25101 | 20/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.46 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6776490 | 0.90 | EDNRB (0.76) | EDNRBEDNRANR1I2KCNE1KCNQ1 | |
| SCHEMBL8703985 | 0.88 | EDNRB (0.62) | EDNRBEDNRANR1I2KCNE1KCNQ1 | |
| SCHEMBL2350734 | 0.86 | EDNRB (0.81) | EDNRBEDNRANR1I2KCNE1KCNQ1 | |
| SCHEMBL6708961 | 0.86 | EDNRB (0.64) | EDNRBEDNRANR1I2KCNE1KCNQ1 | |
| SCHEMBL1068402 | 0.86 | EDNRB (0.81) | EDNRBEDNRANR1I2KCNE1KCNQ1 | |
| SCHEMBL8704342 | 0.85 | EDNRB (0.60) | EDNRBEDNRA | |
| SCHEMBL8109657 | 0.84 | EDNRB (0.84) | EDNRBEDNRA | |
| SCHEMBL8706689 | 0.84 | EDNRB (0.59) | EDNRBEDNRANR1I2KCNE1KCNQ1 | |
| SCHEMBL8701757 | 0.84 | EDNRB (0.59) | EDNRBEDNRANR1I2KCNE1KCNQ1 | |
| SCHEMBL7811183 | 0.82 | EDNRB (0.55) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686369-B1 | α-hydrdroxylic acid derivatives, their production and use | ABBOTT GMBH & CO., KG (DE) | 2004-02-03 | — | — | US | disclosed |