Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 10/20 | 0.59 |
| ▸ | TACR1 | P25103 | 5/20 | 0.59 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798608 | 0.94 | TACR2 (0.54) | TACR2TACR1 | |
| SCHEMBL7873296 | 0.88 | TACR2 (0.63) | TACR2TACR1 | |
| SCHEMBL7812039 | 0.84 | TACR2 (0.58) | TACR2TACR1OPRL1 | |
| SCHEMBL7870014 | 0.83 | TACR2 (0.59) | TACR2TACR1OPRL1 | |
| SCHEMBL7815384 | 0.82 | HTT (0.53) | — | |
| Hydrochloric Acid SCHEMBL7871907 | 0.82 | TACR2 (0.58) | TACR2TACR1OPRL1 | |
| SCHEMBL7802989 | 0.79 | TACR2 (0.59) | TACR2TACR1OPRL1 | |
| SCHEMBL7864552 | 0.79 | TACR2 (0.65) | TACR2TACR1 | |
| SCHEMBL8588638 | 0.78 | TACR2 (0.69) | TACR2TACR1 | |
| SCHEMBL7871908 | 0.78 | TACR2 (0.62) | TACR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773929-B1 | PIPERIDINE DERIVATIVES AS NEUROKININ ANTAGONISTS | SCHERING CORP (US) | 2001-10-31 | — | — | EP | disclosed |
| US-5654316-A | Piperidine derivatives as neurokinin antagonists | SCHERING CORPORATION (US) | 1997-08-05 | — | — | US | disclosed |