Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 12/20 | 0.62 |
| ▸ | TACR1 | P25103 | 9/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6952533 | 0.85 | TACR2 (0.61) | TACR2TACR1SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL9317674 | 0.85 | TACR2 (0.73) | TACR2TACR1 | |
| Hydrochloric Acid SCHEMBL7871923 | 0.81 | TACR2 (0.69) | TACR2TACR1 | |
| SCHEMBL7864552 | 0.81 | TACR2 (0.65) | TACR2TACR1 | |
| SCHEMBL8588638 | 0.80 | TACR2 (0.69) | TACR2TACR1 | |
| SCHEMBL7873214 | 0.79 | TACR1 (0.59) | TACR2TACR1 | |
| Hydrochloric Acid SCHEMBL9317762 | 0.79 | TACR2 (0.65) | TACR2TACR1 | |
| SCHEMBL8479506 | 0.79 | TACR2 (0.72) | TACR2TACR1 | |
| SCHEMBL7811276 | 0.78 | TACR2 (0.59) | TACR2TACR1 | |
| SCHEMBL7802957 | 0.78 | TACR2 (0.66) | TACR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808303-B1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ASTRAZENECA AB (SE) | 2001-06-20 | — | — | EP | disclosed |
| EP-0808303-A1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ZENECA LIMITED (GB) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024582-A1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ZENECA LIMITED (GB) | 1996-08-15 | — | — | WO | disclosed |