Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCD | Q05655 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.44 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.44 |
| ▸ | PRKCG | P05129 | 2/20 | 0.44 |
| ▸ | PRKCB | P05771 | 2/20 | 0.44 |
| ▸ | PRKCA | P17252 | 2/20 | 0.44 |
| ▸ | PRKCH | P24723 | 2/20 | 0.44 |
| ▸ | PRKCI | P41743 | 2/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7811543 | 0.88 | CYP3A4 (0.44) | PRKCDCYP3A4PRKCEPRKD1NFKB1 | |
| SCHEMBL7811496 | 0.82 | CYP3A4 (0.55) | PRKCDCYP3A4PRKCEPRKD1NFKB1 | |
| SCHEMBL7810737 | 0.80 | ROCK2 (0.59) | PRKCDCYP3A4PRKCEPRKD1NFKB1 | |
| SCHEMBL2007210 | 0.80 | ALOX5AP (0.49) | ALOX5APFEN1COMT | |
| SCHEMBL2008831 | 0.80 | ALOX5AP (0.49) | ALOX5APFEN1COMT | |
| SCHEMBL2007211 | 0.80 | ALOX5AP (0.49) | ALOX5APFEN1COMT | |
| SCHEMBL2004580 | 0.80 | ALOX5AP (0.51) | ALOX5APFEN1COMTL3MBTL1 | |
| SCHEMBL2000949 | 0.80 | ALOX5AP (0.51) | ALOX5APFEN1COMTL3MBTL1 | |
| SCHEMBL2000952 | 0.80 | ALOX5AP (0.51) | ALOX5APFEN1COMTL3MBTL1 | |
| SCHEMBL7807342 | 0.79 | ROCK2 (0.58) | PRKCDCYP3A4PRKCEPRKD1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074545-A1 | ISOQUINOLINESULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | Hidaka, Hiroyoshi (JP) | 2001-02-07 | — | — | EP | disclosed |