Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MLNR | O43193 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817381 | 0.91 | PARP1 (0.34) | L3MBTL1MAPK1MLNRALDH1A1KDM4E | |
| SCHEMBL7830154 | 0.78 | IRAK4 (0.35) | MAPK1KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL7445212 | 0.69 | F2 (0.46) | KMT2AMEN1KDM4ESMN1; SMN2TDP1 | |
| SCHEMBL7809457 | 0.68 | F2 (0.41) | F2 | |
| SCHEMBL7819870 | 0.67 | PARP1 (0.41) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7825998 | 0.65 | PFKFB3 (0.44) | KMT2AALDH1A1LMNAGAAPFKFB3 | |
| SCHEMBL7818700 | 0.64 | MEN1 (0.41) | MAPK1KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL7812445 | 0.64 | F2 (0.49) | F2 | |
| SCHEMBL7818112 | 0.64 | S1PR1 (0.47) | KMT2AMEN1MCHR1F2 | |
| SCHEMBL7819938 | 0.62 | F2 (0.37) | MAPK1KDM4EF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027051-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2001-03-07 | — | — | EP | disclosed |
| EP-1027051-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1998048804-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |