Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7818690 | 0.88 | S1PR1 (0.39) | S1PR1MAOBACHEHRH3 | |
| SCHEMBL7818611 | 0.78 | F2 (0.48) | F2S1PR1MAOBACHEHRH3 | |
| SCHEMBL7820796 | 0.77 | HPGD (0.44) | F2ACHEHRH3KDM4E | |
| SCHEMBL7831868 | 0.77 | F2 (0.41) | F2HRH3KDM4E | |
| SCHEMBL7830154 | 0.76 | IRAK4 (0.35) | F2IRAK4MAPK1 | |
| SCHEMBL6172781 | 0.74 | F2 (0.70) | F2 | |
| Oxalic Acid SCHEMBL6173931 | 0.73 | F2 (0.67) | F2 | |
| SCHEMBL7818365 | 0.73 | S1PR1 (0.45) | F2S1PR1MAOBACHEHRH3 | |
| SCHEMBL6960955 | 0.73 | F2 (0.42) | F2HRH3KDM4EMAPK1 | |
| SCHEMBL7817381 | 0.69 | PARP1 (0.34) | F2HRH3KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027051-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2001-03-07 | — | — | EP | claimed |
| EP-1027051-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-08-16 | — | — | EP | claimed |
| WO-1998048804-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | claimed |