Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7807535 | 0.93 | ALOX5 (0.87) | ALOX5 | |
| SCHEMBL2436940 | 0.92 | ALOX5 (1.00) | ALOX5 | |
| Hydrochloric Acid SCHEMBL8178848 | 0.91 | ALOX5 (0.98) | ALOX5 | |
| SCHEMBL8409121 | 0.91 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL8166712 | 0.91 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL7815037 | 0.91 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL8173880 | 0.89 | ALOX5 (0.84) | ALOX5 | |
| SCHEMBL8783922 | 0.88 | ALOX5 (0.80) | ALOX5 | |
| SCHEMBL8173882 | 0.85 | ALOX5 (0.80) | ALOX5 | |
| SCHEMBL8787947 | 0.85 | ALOX5 (1.00) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787127-B1 | 5-LIPOXYGENASE INHIBITORS | PFIZER (US) | 2001-01-03 | — | — | EP | disclosed |
| US-6063928-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, CARDIOTONIC AGENTS | PFIZER INC (US) | 2000-05-16 | — | — | US | disclosed |
| US-5883106-A | 5-lipoxygenase inhibitors | PFIZER INC. (US) | 1999-03-16 | — | — | US | disclosed |