SCHEMBL7812010

SCHEMBL7812010

CC(C)(C)C(O)C(C)(C)C(O)C(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2164167 0.82 TSHR (0.41) TSHR
SCHEMBL4436411 0.72 TSHR (0.35) TSHR
SCHEMBL14663990 0.69 TSHR (0.33) TSHR
SCHEMBL12219511 0.69 TSHR (0.33) TSHR
SCHEMBL440846 0.69 TSHR (0.33) TSHR
SCHEMBL12219513 0.69 TSHR (0.33) TSHR
SCHEMBL7990072 0.69 LMNA (0.44) TSHR
SCHEMBL205358 0.67
SCHEMBL9239211 0.67 TSHR (0.38) TSHR
SCHEMBL8526845 0.67 TSHR (0.32) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0779293-B1 1,2-Dioxetane derivatives as chemiluscent agents FUJIREBIO KK (JP) 2001-10-24 EP disclosed
EP-0635512-B1 Cyclic phosphites as polymer stabilizers GEN ELECTRIC (US) 2000-03-01 EP disclosed
US-5877333-A 1,2-dioxetane derivatives FUJIREBIO INC. (JP) 1999-03-02 US disclosed
US-5731445-A 1,2- Dioxetane derivatives FUJIREBIO INC. (JP) 1998-03-24 US disclosed
EP-0779293-A1 1,2-Dioxetane derivatives as chemiluscent agents FUJIREBIO Inc. (JP) 1997-06-18 EP disclosed
US-5464889-A Stabilization of thermoplastic resins GENERAL ELECTRIC COMPANY (US) 1995-11-07 US disclosed
EP-0635512-A1 Cyclic phosphites as polymer stabilizers GENERAL ELECTRIC COMPANY (US) 1995-01-25 EP disclosed