SCHEMBL7812480

SCHEMBL7812480

Cc1cc(N)cc(-c2ccc[nH]2)c1N(CCO)CCO

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CDK2 P24941 4/20 0.32
PDE10A Q9Y233 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7800694 0.85 MEN1 (0.32)
SCHEMBL7812221 0.78 MEN1 (0.33) CDK2
SCHEMBL7812329 0.77 MAPT (0.36) CDK2
SCHEMBL7808698 0.77 ALDH1A1 (0.36) CDK2
SCHEMBL7808739 0.77 ALDH1A1 (0.34) CDK2
SCHEMBL7459373 0.76 PDE10A (0.30) PDE10A
SCHEMBL7805963 0.75 CDK2 (0.38) CDK2PDE10A
SCHEMBL7809761 0.73 NPC1 (0.40)
SCHEMBL7807702 0.73 ADORA2A (0.39)
SCHEMBL7805944 0.73 ALDH1A1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0943614-B1 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives WELLA AG (DE) 2001-12-12 EP disclosed
US-6042620-A FOR DYEING KERATIN FIBERS SUCH AS HAIR WELLA AG (DE) 2000-03-28 US disclosed
EP-0943614-A2 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives Wella Aktiengesellschaft (DE) 1999-09-22 EP disclosed