SCHEMBL78126

SCHEMBL78126

C=C(C)C(=O)NC(=O)C(=C)C

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
TDP1 Q9NUW8 3/20 0.44
TGFBR1 P36897 1/20 0.41
KDM4E B2RXH2 2/20 0.39
KDM5B Q9UGL1 1/20 0.39
RXFP1 Q9HBX9 1/20 0.37
HSD17B10 Q99714 1/20 0.33
CA2 P00918 1/20 0.33
PTGS1 P23219 1/20 0.33
MMP12 P39900 1/20 0.33
LMNA P02545 1/20 0.33
CRBN Q96SW2 1/20 0.33
NFKB1 P19838 1/20 0.32
TSHR P16473 1/20 0.31
THPO P40225 1/20 0.31
FFAR3 O14843 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31
TAS2R38 P59533 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7171041 1.00 ALDH1A1 (0.45) ALDH1A1TDP1TGFBR1KDM4EKDM5B
SCHEMBL10408126 0.91 ALDH1A1 (0.39) ALDH1A1TDP1TGFBR1KDM4EKDM5B
SCHEMBL28188026 0.87
SCHEMBL6802232 0.87
SCHEMBL139723 0.87
SCHEMBL6852988 0.87 ALDH1A1 (0.41) ALDH1A1TDP1TGFBR1KDM4ERXFP1
SCHEMBL11125396 0.87 ALDH1A1 (0.41) ALDH1A1TDP1TGFBR1KDM4ERXFP1
SCHEMBL29977919 0.86 ALDH1A1 (0.36) ALDH1A1TDP1TGFBR1KDM4EKDM5B
SCHEMBL3164394 0.84
SCHEMBL27757052 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5628 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4304842-B1 METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES ALCON INC (CH) 2026-05-06 EP claimed
US-20250276007-A1 CARBAMOYLPHENYLBORONIC ACID-CONTAINING ACRYLIC MONOMERS AND USES THEREOF ALCON INC (CH) 2025-09-04 US claimed
US-12111443-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2024-10-08 US claimed
EP-4121802-B1 HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES ALCON INC (CH) 2024-07-17 EP claimed
EP-4395730-A1 DISSOLVABLE SOLID STRUCTURE COMPRISING FIRST AND SECOND POLYMERIC STRUCTURANTS The Procter & Gamble Company (US) 2024-07-10 EP claimed
CN-118137133-A Low-loss radome structure 深圳市飞思通信技术有限公司 2024-06-04 CN claimed
EP-3635450-B1 SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-05-08 EP claimed
EP-4121801-B1 INSERT MATERIALS WITH HIGH OXYGEN PERMEABILITY AND HIGH REFRACTIVE INDEX ALCON INC (CH) 2024-04-17 EP claimed
US-11926689-B2 Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof ALCON INC. (CH) 2024-03-12 US claimed
EP-4118134-B1 PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS ALCON INC (CH) 2024-02-28 EP claimed
US-4661434-A PHOTORESISTS FUJI PHOTO FILM CO., LTD. (JP) 1987-04-28 US claimed
US-4584260-A 4,41-BIS(DIALKYLAMINO)BENZOPHENONE A BENZOPHENONE, 1,3,4-OXADIAZOLE COMPOUND, AROMATIC HALOGENATED SULFONE, QUINAZOLINE AND TRIAZINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1986-04-22 US claimed
EP-0137228-A2 Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1985-04-17 EP claimed
US-4302522-A FOLLOWED BY IN SITU PHOTOPOLYMERIZATION GARNETT JOHN L 1981-11-24 US claimed
US-4259223-A ADDUCT WITH BIOPOLYMER; IMMUNOASSAY CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1981-03-31 US claimed
US-4256782-A IRRADIATING A POLYMERIZABLE COMPOUND ON THE SURFACE KANSAI PAINT CO., LTD. (JP) 1981-03-17 US claimed
US-4139391-A AN UNSATURATED COMPOUND, A PHOTOINITIATOR AND AN ACRYLIC OR METHACRYLIC ACID COPOLYMER WITH AN ACRYLIC OR METHACRYLIC ESTER, PHOTORESISTS, ALKALI RESISTANCE FUJI PHOTO FILM CO., LTD. (JP) 1979-02-13 US claimed
US-4097420-A Method for preparation of macroporous amphoteric ion exchangers with highly crosslinked hydrophilic polymeric matrix CESKOSLOVENSKA AKADEMIE VED (CS) 1978-06-27 US claimed
US-4025348-A DI-UNSATURATED COMPOUND, POLYMER WITH TETRAHYDROFURFURYL OR N-ALKOXYMETHYLCARBAMOYL GROUPS, DIEPOXIDE, SENSITIZER, CURING AGENT HITACHI CHEMICAL COMPANY, LTD. (JA) 1977-05-24 US claimed
US-3997482-A Hydrophilic polymeric carriers of biologically active compounds and method of preparing the same CESKOSLOVENSKA AKADEMIE VED (CS) 1976-12-14 US claimed