Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TOP1 | P11387 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27960801 | 0.80 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1LMNAHPGDTSHR | |
| SCHEMBL9188543 | 0.80 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1TOP1LMNAHPGD | |
| SCHEMBL12939880 | 0.80 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1LMNAHPGDTSHR | |
| SCHEMBL21985460 | 0.79 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1TOP1LMNAHPGD | |
| SCHEMBL19976649 | 0.79 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1LMNAHPGDTSHR | |
| SCHEMBL22882940 | 0.79 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1TOP1LMNAHPGD | |
| SCHEMBL23585046 | 0.79 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1TOP1LMNAHPGD | |
| SCHEMBL7632891 | 0.78 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1LMNAHPGDPKM | |
| SCHEMBL20216016 | 0.77 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1TOP1LMNAHPGD | |
| SCHEMBL12522822 | 0.77 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1LMNAHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077970-A1 | 11-ARYL-BENZO(B)NAPHTHO(2,3-D)FURANS AND 11-ARYL-BENZO(B)NAPHTHO(2,3-D)THIOPHENES USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058521-A1 | 11-ARYL-BENZO[B]NAPHTHO[2,3-D]FURANS AND 11-ARYL-BENZO[B]NAPHTHO[2,3-D]THIOPHENES USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-11-18 | — | — | WO | disclosed |