Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | BLM | P54132 | 5/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.49 |
| ▸ | THRB | P10828 | 3/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21881191 | 0.97 | CYP2D6 (0.49) | CYP2D6LMNABLMCHRM2CHRM1 | |
| SCHEMBL21881472 | 0.97 | CYP2D6 (0.49) | CYP2D6LMNABLMCHRM2CHRM1 | |
| SCHEMBL21881383 | 0.95 | CYP2D6 (0.48) | CYP2D6LMNABLMCHRM2CHRM1 | |
| SCHEMBL27103875 | 0.83 | SLC6A2 (0.50) | CYP2D6CYP1A2MEN1KMT2AHTT | |
| SCHEMBL23349257 | 0.83 | SLC6A3 (0.51) | LMNAMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL21881386 | 0.83 | CYP19A1 (0.44) | CYP2D6LMNABLMCHRM2CHRM1 | |
| SCHEMBL14068457 | 0.83 | SLC6A3 (0.51) | LMNAMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL25435834 | 0.82 | TSHR (0.40) | CYP2D6LMNACHRM2CHRM1PMP22 | |
| SCHEMBL21881480 | 0.81 | TSHR (0.46) | CYP2D6LMNACHRM2CHRM1MEN1 | |
| SCHEMBL21881471 | 0.81 | TSHR (0.46) | CYP2D6LMNACHRM2CHRM1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |