Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.50 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 4/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9249296 | 1.00 | DNM1 (0.52) | DNM1LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL9253135 | 1.00 | DNM1 (0.52) | DNM1LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL17386385 | 1.00 | DNM1 (0.52) | DNM1LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL3633977 | 1.00 | DNM1 (0.52) | DNM1LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL6435941 | 1.00 | DNM1 (0.52) | DNM1LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL8974845 | 1.00 | DNM1 (0.52) | DNM1LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL10335702 | 0.97 | LCK (0.52) | DNM1LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL8862993 | 0.97 | LCK (0.52) | DNM1LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL21799217 | 0.97 | LCK (0.52) | DNM1LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL9533300 | 0.97 | LCK (0.52) | DNM1LCKPPARDZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077929-A1 | 2,3,5-SUBSTITUTED BIPHENYLS USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999061410-A1 | 2,3,5-SUBSTITUTED BIPHENYLS USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-12-02 | — | — | WO | disclosed |
| US-5432237-A | Radically polymerizable composition | SHOWA DENKO K.K. (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0399463-B1 | Radically polymerizable composition | SHOWA DENKO KK (JP) | 1994-02-23 | — | — | EP | disclosed |
| EP-0399463-A2 | Radically polymerizable composition | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1990-11-28 | — | — | EP | disclosed |