Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAT1 | P18440 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | NSD2 | O96028 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | GFER | P55789 | 1/20 | 0.68 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | TTR | P02766 | 3/20 | 0.67 |
| ▸ | IGF1R | P08069 | 2/20 | 0.67 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | PIM1 | P11309 | 2/20 | 0.62 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.62 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14564270 | 1.00 | NAT1 (1.00) | NAT1TDP1KDM4ENSD2POLB | |
| SCHEMBL1249157 | 1.00 | NAT1 (1.00) | NAT1TDP1KDM4ENSD2POLB | |
| SCHEMBL1249158 | 1.00 | NAT1 (1.00) | NAT1TDP1KDM4ENSD2POLB | |
| SCHEMBL7985096 | 1.00 | NAT1 (1.00) | NAT1TDP1KDM4ENSD2POLB | |
| SCHEMBL20637542 | 0.84 | NAT1 (0.73) | NAT1TDP1KDM4ENSD2POLB | |
| SCHEMBL19120542 | 0.84 | NAT1 (0.73) | NAT1TDP1KDM4ENSD2POLB | |
| SCHEMBL15421776 | 0.84 | NAT1 (0.72) | NAT1TDP1KDM4ENSD2POLB | |
| SCHEMBL3425968 | 0.84 | NAT1 (1.00) | NAT1TDP1PIM1GSK3B | |
| SCHEMBL14860908 | 0.84 | TDP1 (1.00) | NAT1TDP1GAAMAPTMAPK1 | |
| SCHEMBL14860911 | 0.84 | TDP1 (1.00) | NAT1TDP1GAAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001002377-A9 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORP (US) | 2001-10-11 | — | — | WO | disclosed |
| EP-1109796-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | Geron Corporation (US) | 2001-06-27 | — | — | EP | disclosed |
| WO-2001002377-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORPORATION (US) | 2001-01-11 | — | — | WO | disclosed |