SCHEMBL781323

SCHEMBL781323

Fc1cnc(F)c(F)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29384015 1.00
SCHEMBL15624387 0.77 GABRG2 (0.43)
SCHEMBL20714876 0.74
SCHEMBL25727294 0.74
SCHEMBL2696903 0.72 VRK1 (0.40)
SCHEMBL23780810 0.72
SCHEMBL1064397 0.72
SCHEMBL781371 0.72
SCHEMBL502594 0.72
SCHEMBL19437189 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 348 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240242971-A1 NITROGEN-CONTAINING AROMATIC OR RING STRUCTURE MOLECULES FOR PLASMA ETCH AND DEPOSITION AMERICAN AIR LIQUIDE, INC. 2024-07-18 US claimed
WO-2024145170-A1 NITROGEN-CONTAINING AROMATIC OR RING STRUCTURE MOLECULES FOR PLASMA ETCH AND DEPOSITION L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2024-07-04 WO claimed
CN-114014801-B Green production process of 2, 3-difluoro-5-chloropyridine with low single impurity content 江苏丰山生化科技有限公司 2024-06-21 CN claimed
CN-115084655-A Electrolyte, preparation method thereof and lithium metal battery containing electrolyte 蜂巢能源科技(无锡)有限公司 2022-09-20 CN claimed
CN-114014801-A Green production process of 2, 3-difluoro-5-chloropyridine with low single impurity content 江苏丰山集团股份有限公司 2022-02-08 CN claimed
EP-0178260-B1 PROCESS FOR THE PREPARATION OF FLUORINATED PYRIDINE DERIVATIVES CIBA-GEIGY AG (CH) 1990-05-16 EP claimed
US-12642026-B2 Nitrogen-containing aromatic or ring structure molecules for plasma etch and deposition AMERICAN AIR LIQUIDE, INC. (US) 2026-05-26 US disclosed
US-20260137680-A1 NOVEL COMPOUNDS SITRYX THERAPEUTICS LTD (GB) 2026-05-21 US disclosed
US-12630570-B2 Organometallic adduct compound and method of manufacturing integrated circuit device by using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2026-05-19 US disclosed
US-20250339541-A1 ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS AVILAR THERAPEUTICS, INC. (US) 2025-11-06 US disclosed
US-20250257052-A1 GLP-1 RECEPTOR AGONISTS AND USES THEREOF PFIZER INC. (US) 2025-08-14 US disclosed
US-20250213699-A1 ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS AVILAR THERAPEUTICS, INC. (US) 2025-07-03 US disclosed
EP-4562006-A1 N-HETEROCYLIC GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE Carmot Therapeutics, Inc. (US) 2025-06-04 EP disclosed
EP-0556737-A1 Process for the preparation of substituted 2,3-difluoro-pyridines HOECHST AKTIENGESELLSCHAFT (DE) 1993-08-25 EP disclosed
EP-0178260-B1 PROCESS FOR THE PREPARATION OF FLUORINATED PYRIDINE DERIVATIVES CIBA-GEIGY AG (CH) 1990-05-16 EP disclosed
US-4891108-A CHLORINATION WHILE HEATING AND ULTRAVIOLET RADIATING THE DOW CHEMICAL COMPANY (US) 1990-01-02 US disclosed
US-4822887-A Preparation of difluoropyridine compounds THE DOW CHEMICAL COMPANY (US) 1989-04-18 US disclosed
US-4684734-A Method for manufacture or organic fluorine compounds NIPPON SHOKUBAI KK CO., LTD. (JP) 1987-08-04 US disclosed
EP-0146924-A2 Preparation of difluorpyridine compounds THE DOW CHEMICAL COMPANY (US) 1985-07-03 EP disclosed
EP-0120575-A1 Organic fluorine compounds Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) 1984-10-03 EP disclosed