SCHEMBL7813575

SCHEMBL7813575

COC(=O)COC1c2ccccc2COc2ccc(OCc3ccc4cccc(Cl)c4n3)cc21

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 7/20 0.39
CYSLTR1 Q9Y271 1/20 0.36
LTB4R Q15722 2/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7809294 0.86 ALOX5AP (0.42) ALOX5APCYSLTR1LTB4R
SCHEMBL7813341 0.79 LTB4R (0.48) ALOX5APCYSLTR1LTB4R
SCHEMBL7809755 0.78 LTB4R (0.41) ALOX5APCYSLTR1LTB4R
SCHEMBL7802773 0.77 LTB4R (0.40) ALOX5APCYSLTR1LTB4R
SCHEMBL7809578 0.74 LTB4R (0.41) ALOX5APCYSLTR1LTB4R
SCHEMBL7808107 0.73 ALOX5AP (0.40) ALOX5APCYSLTR1LTB4R
SCHEMBL7813383 0.73 LTB4R (0.43) ALOX5APCYSLTR1LTB4RMEN1KMT2A
SCHEMBL7809813 0.70 TBXA2R (0.42)
SCHEMBL7801832 0.69 LTB4R (0.39) ALOX5APCYSLTR1LTB4RMEN1KMT2A
SCHEMBL7810463 0.69 TBXA2R (0.45) CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0685478-B1 QUINOLINE DERIVATIVES UBE INDUSTRIES (JP) 2001-10-24 EP claimed