Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7813619 | 1.00 | ALDH1A1 (0.55) | ALDH1A1HPGDMAPTSMN1; SMN2GAA | |
| SCHEMBL7813948 | 0.94 | ALDH1A1 (0.62) | ALDH1A1HPGDMAPTSMN1; SMN2GAA | |
| SCHEMBL7813951 | 0.94 | ALDH1A1 (0.62) | ALDH1A1HPGDMAPTSMN1; SMN2GAA | |
| SCHEMBL7822120 | 0.84 | MEN1 (0.64) | ALDH1A1HPGDMAPTSMN1; SMN2GAA | |
| SCHEMBL7822118 | 0.84 | MEN1 (0.64) | ALDH1A1HPGDMAPTSMN1; SMN2GAA | |
| SCHEMBL7828683 | 0.83 | CYP3A4 (0.57) | ALDH1A1HPGDMAPTSMN1; SMN2GAA | |
| SCHEMBL7828680 | 0.83 | CYP3A4 (0.57) | ALDH1A1HPGDMAPTSMN1; SMN2GAA | |
| SCHEMBL7828248 | 0.83 | ALDH1A1 (0.59) | ALDH1A1HPGDMAPTSMN1; SMN2GAA | |
| SCHEMBL7828244 | 0.83 | ALDH1A1 (0.59) | ALDH1A1HPGDMAPTSMN1; SMN2GAA | |
| SCHEMBL12015295 | 0.81 | MAPT (0.54) | ALDH1A1HPGDMAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |