Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 8/20 | 0.53 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.53 |
| ▸ | GRM5 | P41594 | 2/20 | 0.53 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | GRM8 | O00222 | 2/20 | 0.53 |
| ▸ | GRM6 | O15303 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ARG1 | P05089 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13319985 | 1.00 | GRM4 (0.53) | GRM4GRM2CYP1A2CYP2C19GRM3 | |
| SCHEMBL14095294 | 0.82 | GRM4 (0.55) | GRM4GRM2CYP1A2CYP2C19GRM3 | |
| SCHEMBL2905580 | 0.81 | GRM4 (0.53) | GRM4GRM2CYP1A2CYP2C19GRM3 | |
| SCHEMBL28114711 | 0.79 | ARG1 (0.55) | GRM4GRM2CYP1A2CYP2C19GRM3 | |
| SCHEMBL27271003 | 0.78 | ARG1 (0.54) | GRM4GRM2CYP1A2CYP2C19GRM3 | |
| SCHEMBL19575920 | 0.78 | ARG1 (0.54) | GRM4GRM2CYP1A2CYP2C19GRM3 | |
| SCHEMBL3065795 | 0.75 | ANPEP (0.44) | GRM2GRM5GRM1TDP1ALDH1A1 | |
| SCHEMBL19548709 | 0.75 | ARG1 (0.82) | GRM4GRM2CYP1A2CYP2C19GRM3 | |
| Hydrochloric Acid SCHEMBL19548598 | 0.74 | ARG1 (0.80) | ARG1 | |
| SCHEMBL19548552 | 0.73 | ARG1 (0.68) | ARG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |