SCHEMBL7814566

SCHEMBL7814566

[O-][n+]1ncccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6922206 0.65
SCHEMBL4963192 0.65
SCHEMBL8632065 0.56
SCHEMBL8318561 0.56
Hydrochloric Acid SCHEMBL8636532 0.54
Hydrochloric Acid SCHEMBL362152 0.41
Hydrochloric Acid SCHEMBL29453380 0.41
Hydrochloric Acid SCHEMBL72335 0.41
Benzene SCHEMBL23388152 0.39 TSHR (0.60)
Benzene SCHEMBL1572970 0.39

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024099992-A1 TRIAZINONE DERIVATIVES AS NLRP3 INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2024-05-16 WO claimed
CN-108752349-A A kind of environmental type priming and preparation method thereof 中国工程物理研究院化工材料研究所 2018-11-06 CN claimed
CN-1179753-C Contraceptive compositions contaiing antiprogesting and progestinic 2004-12-15 CN claimed
CN-1474652-A Substituted 4,5-dihydro-1,2,4-triazin -6-ones, 1,2,4-triazin-6-ones, and their use as fungicides and insecticides �ݶ�ũ�����޹�˾ 2004-02-11 CN claimed
CN-1291892-A Substituted oxoazaheterocyclyl factor Xa inhibitors AWENTIS PHARMACEUTICAL INC (US) 2001-04-18 CN claimed
WO-1999007352-A2 METHOD FOR PROMOTING EXPRESSION OF LDL RECEPTOR GENE SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1999-02-18 WO claimed
US-4338441-A CYCLIZATION OF AMIDINOUREA OR AMIDINOTHIOUREA WITH ACTIVE METHYLIDENE COMPOUND WILLIAM H. RORER, INC. (US) 1982-07-06 US claimed
WO-2024099996-A1 TRIAZINONE DERIVATIVES AS NLRP3 INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2024-05-16 WO disclosed
CN-117820320-A Preparation method of heat-resistant energetic material PTO 南京理工大学 2024-04-05 CN disclosed
EP-4337652-A1 NLRP3 INHIBITORS F. Hoffmann-La Roche AG (CH) 2024-03-20 EP disclosed
US-11247997-B2 Compound and preparation and application thereof INSTITUTE OF CHEMICAL MATERIALS OF CHINA ACADEMY OF ENGINEERING AND PHYSICS (CN) 2022-02-15 US disclosed
EP-3917915-A1 1,2,4-TRIAZIN-3(2H)-ONE COMPOUNDS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES Bayer Aktiengesellschaft (DE) 2021-12-08 EP disclosed
US-20210155624-A1 COMPOUND AND PREPARATION AND APPLICATION THEREOF INSTITUTE OF CHEMICAL MATERIALS OF CHINA ACADEMY OF ENGINEERING AND PHYSICS (CN) 2021-05-27 US disclosed
US-4452980-A DIARRHEA WILLIAM H. RORER, INC. (US) 1984-06-05 US disclosed
US-4387225-A Heterocyclic alkylene triazinones WILLIAM H. RORER, INC. (US) 1983-06-07 US disclosed
EP-0078841-A1 HETEROCYCLIC ALKYLENE TRIAZINONES RORER INTERNATIONAL (OVERSEAS) INC. (US) 1983-05-18 EP disclosed
WO-1982004050-A1 HETEROCYCLIC ALKYLENE TRIAZINONES RORER INT OVERSEAS (US) 1982-11-25 WO disclosed
US-4338441-A CYCLIZATION OF AMIDINOUREA OR AMIDINOTHIOUREA WITH ACTIVE METHYLIDENE COMPOUND WILLIAM H. RORER, INC. (US) 1982-07-06 US disclosed
US-4246409-A ANTIDIARRHEAL AGENTS WILLIAM H. RORER, INC. (US) 1981-01-20 US disclosed
US-4225315-A Triazinones from amidinoureas WILLIAM H. RORER, INC. (US) 1980-09-30 US disclosed