Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CETP | P11597 | 3/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25613602 | 0.98 | L3MBTL1 (0.50) | TSHRL3MBTL1TDP1CETPLTA4H | |
| SCHEMBL941253 | 0.90 | TSHR (0.56) | TSHRL3MBTL1TDP1CETPLTA4H | |
| SCHEMBL11995970 | 0.89 | L3MBTL1 (0.58) | TSHRL3MBTL1TDP1CETPLTA4H | |
| SCHEMBL21081916 | 0.89 | L3MBTL1 (0.58) | TSHRL3MBTL1TDP1CETPLTA4H | |
| SCHEMBL7641859 | 0.89 | L3MBTL1 (0.58) | TSHRL3MBTL1TDP1CETPLTA4H | |
| SCHEMBL7120703 | 0.89 | L3MBTL1 (0.58) | TSHRL3MBTL1TDP1CETPLTA4H | |
| SCHEMBL6685708 | 0.89 | L3MBTL1 (0.58) | TSHRL3MBTL1TDP1CETPLTA4H | |
| SCHEMBL2886385 | 0.89 | L3MBTL1 (0.58) | TSHRL3MBTL1TDP1CETPLTA4H | |
| SCHEMBL14526009 | 0.89 | L3MBTL1 (0.58) | TSHRL3MBTL1TDP1CETPLTA4H | |
| SCHEMBL16057438 | 0.89 | L3MBTL1 (0.58) | TSHRL3MBTL1TDP1CETPLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124810-A1 | 2-AMINO-THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA & UPJOHN S.p.A. (IT) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026202-A1 | 2-AMINO-THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2000-05-11 | — | — | WO | disclosed |