SCHEMBL7814756

SCHEMBL7814756

O=C(O)CCCCCN=Cc1ccccc1O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 7/20 0.76
CA2 P00918 6/20 0.76
CA9 Q16790 5/20 0.76
KDM4E B2RXH2 3/20 0.62
GAA P10253 1/20 0.48
HTT P42858 1/20 0.48
CA1 P00915 1/20 0.47
ALDH1A1 P00352 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
POLB P06746 1/20 0.45
CTRC Q99895 1/20 0.44
DUSP3 P51452 1/20 0.44
PTPN5 P54829 1/20 0.44
PTPN11 Q06124 1/20 0.44
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44
KMT2A Q03164 1/20 0.44
MAPT P10636 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
HDAC3 O15379 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27592075 1.00 CA12 (0.76) CA12CA2CA9KDM4EGAA
SCHEMBL7814753 1.00 CA12 (0.76) CA12CA2CA9KDM4EGAA
SCHEMBL10877620 0.87 CA2 (0.70) CA12CA2CA9KDM4EGAA
SCHEMBL1300528 0.87 CA12 (1.00) CA12CA2CA9KDM4EGAA
SCHEMBL14353888 0.87 CA12 (1.00) CA12CA2CA9KDM4EGAA
SCHEMBL24435598 0.87 CA12 (1.00) CA12CA2CA9KDM4EGAA
SCHEMBL1300527 0.87 CA12 (1.00) CA12CA2CA9KDM4EGAA
SCHEMBL14353944 0.87 CA12 (1.00) CA12CA2CA9KDM4EGAA
SCHEMBL15456115 0.87 CA12 (1.00) CA12CA2CA9KDM4EGAA
SCHEMBL14353945 0.87 CA12 (1.00) CA12CA2CA9KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed