SCHEMBL7814930

SCHEMBL7814930

CC(=O)NC[C@H]1CN(c2ccc(N3CCC(O[Si](C)(C)C(C)(C)C)C3)c(F)c2)C(=O)O1

nearest known ligand 0.67

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.67
MAOB P27338 4/20 0.67
PTGS1 P23219 2/20 0.67
SDHA P31040 2/20 0.67
LMNA P02545 1/20 0.67
CALML3 P27482 1/20 0.67
F10 P00742 7/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7814926 1.00 MAOA (0.67) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7814928 1.00 MAOA (0.67) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7811331 0.93 MAOA (0.68) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7811335 0.93 MAOA (0.68) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6335892 0.89 MAOA (0.65) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7807712 0.89 CALML3 (0.51) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7807715 0.89 CALML3 (0.51) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7807718 0.89 CALML3 (0.51) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7082696 0.89 CALML3 (0.51) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7082698 0.89 CALML3 (0.51) MAOAMAOBPTGS1SDHALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0788498-B1 PHENYLOXAZOLIDINONE ANTIMICROBIALS UPJOHN CO (US) 2001-08-16 EP disclosed
WO-1996013502-A1 PHENYLOXAZOLIDINONE ANTIMICROBIALS PHARMACIA & UPJOHN COMPANY (US) 1996-05-09 WO disclosed