Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409870 | 0.90 | XIAP (0.56) | XIAPACE | |
| SCHEMBL16464700 | 0.90 | XIAP (0.56) | XIAPACE | |
| SCHEMBL16465568 | 0.90 | XIAP (0.56) | XIAPACE | |
| SCHEMBL9409863 | 0.90 | XIAP (0.56) | XIAPACE | |
| SCHEMBL3729400 | 0.87 | ACE (0.57) | XIAPACE | |
| SCHEMBL7269341 | 0.87 | ACE (0.57) | XIAPACE | |
| SCHEMBL10292602 | 0.86 | NOTUM (0.53) | XIAP | |
| SCHEMBL15765599 | 0.86 | NOTUM (0.53) | XIAP | |
| SCHEMBL3265355 | 0.85 | XIAP (0.52) | XIAPACE | |
| SCHEMBL3722659 | 0.84 | XIAP (0.82) | XIAPACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114822-A2 | Indoles and tetrahydroisoquinolines containing alpha-keto oxadiazoles as serine protease inhibitors | Cortech Inc. (US) | 2001-07-11 | — | — | EP | disclosed |
| US-6100238-A | USEFUL AS INHIBITORS OF HUMAN NEUTROPHIL ELASTASE (HNE) FOR THE TREATMENT OF HNE-MEDIATED PROCESSES IMPLICATED IN CONDITIONS SUCH AS ADULT RESPIRATORY DISTRESS SYNDROME, SEPTIC SHOCK AND MULTIPLE ORGAN FAILURE | CORTECH INC. (US) | 2000-08-08 | — | — | US | disclosed |