Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 9/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 1/20 | 0.62 |
| ▸ | THPO | P40225 | 1/20 | 0.62 |
| ▸ | MTOR | P42345 | 1/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22007921 | 0.90 | MEN1 (0.64) | RORCMEN1KMT2AMAPTLMNA | |
| SCHEMBL15668418 | 0.89 | RORC (0.68) | RORCMEN1KMT2AMAPTLMNA | |
| SCHEMBL403214 | 0.86 | RORC (0.73) | RORCMEN1KMT2AMAPTLMNA | |
| SCHEMBL402139 | 0.85 | MAPT (0.77) | RORCMEN1KMT2AMAPTLMNA | |
| SCHEMBL7130662 | 0.85 | RORC (0.73) | RORCMEN1KMT2AMAPTLMNA | |
| SCHEMBL8042285 | 0.83 | MAPT (0.62) | RORCMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL16489011 | 0.83 | MYC (0.60) | RORCMEN1KMT2AMAPTLMNA | |
| SCHEMBL8060482 | 0.82 | RORC (0.66) | RORCMEN1KMT2AMAPTLMNA | |
| SCHEMBL18146442 | 0.81 | RORC (0.81) | RORCMEN1KMT2AMAPTLMNA | |
| SCHEMBL19148563 | 0.81 | RORC (0.67) | RORCMEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |