SCHEMBL7814979

SCHEMBL7814979

CC(=O)NC[C@H]1CN(c2ccc(N3CC(C(=O)CO)C3)c(F)c2)C(=O)O1

nearest known ligand 0.73

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.73
MAOB P27338 5/20 0.73
PTGS1 P23219 2/20 0.73
SDHA P31040 2/20 0.73
LMNA P02545 1/20 0.73
CALML3 P27482 1/20 0.73
F10 P00742 5/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7814986 1.00 MAOA (0.73) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6993651 0.92 MAOB (0.75) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6993645 0.92 MAOB (0.75) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6337460 0.91 MAOA (0.70) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7805434 0.88 MAOA (0.75) MAOAMAOBPTGS1SDHALMNA
SCHEMBL14879976 0.88 MAOA (0.78) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6615781 0.88 MAOA (0.78) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7811167 0.88 MAOA (0.78) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7815072 0.88 MAOA (0.78) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7811069 0.88 MAOA (0.78) MAOAMAOBPTGS1SDHALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0788498-B1 PHENYLOXAZOLIDINONE ANTIMICROBIALS UPJOHN CO (US) 2001-08-16 EP disclosed
CN-1068325-C phenyl oxazolidinone antibacterial agents PHARMACIA & UPJOHN CO LLC (US) 2001-07-11 CN disclosed
CN-1162312-A Phenyloxazolidinone antimicrobials PHARMACIA & UPJOHN CO LLC (US) 1997-10-15 CN disclosed