Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4195994 | 0.91 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL4192411 | 0.83 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL4186240 | 0.83 | PTGS2 (0.60) | PTGS2PTGS1 | |
| SCHEMBL4189050 | 0.82 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL4188414 | 0.82 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL4186365 | 0.82 | PTGS2 (0.59) | PTGS2PTGS1 | |
| SCHEMBL4191872 | 0.81 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL4186267 | 0.81 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL4192089 | 0.81 | PTGS2 (0.60) | PTGS2PTGS1 | |
| SCHEMBL4187463 | 0.80 | PTGS2 (0.65) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124804-A1 | PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-08-22 | — | — | EP | claimed |
| WO-2000024719-A1 | PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2000-05-04 | — | — | WO | claimed |
| EP-1124804-A1 | PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000024719-A1 | PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2000-05-04 | — | — | WO | disclosed |