Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 17/20 | 0.51 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7816665 | 0.98 | ALK (0.52) | ALKPDK4CNR1NR1H2 | |
| SCHEMBL1755890 | 0.92 | ALK (0.49) | ALKPDK4CNR1 | |
| SCHEMBL896882 | 0.90 | ALK (0.62) | ALK | |
| SCHEMBL7813080 | 0.88 | ALK (0.54) | ALKPDK4CNR1NR1H2 | |
| SCHEMBL7806462 | 0.88 | ALK (0.55) | ALKPDK4CNR1 | |
| SCHEMBL16776103 | 0.87 | ALK (0.54) | ALKPDK4 | |
| SCHEMBL898566 | 0.87 | ALK (0.63) | ALK | |
| SCHEMBL7807827 | 0.84 | ALK (0.60) | ALK | |
| SCHEMBL7815269 | 0.82 | ALK (0.57) | ALK | |
| SCHEMBL897569 | 0.82 | ALK (0.60) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010143664-A1 | TETRACYCLIC COMPOUND | 中外製薬株式会社 (JP) | 2010-12-16 | — | — | WO | disclosed |