SCHEMBL7815375

SCHEMBL7815375

CO[C]1C(OC)=Cc2ccccc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25A P30304 4/20 0.42
CDC25B P30305 4/20 0.42
PTPN1 P18031 1/20 0.42
IDO1 P14902 1/20 0.42
PTGS2 P35354 1/20 0.37
KDM4E B2RXH2 2/20 0.37
ALDH1A1 P00352 2/20 0.37
MAPT P10636 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
MAP2K7 O14733 1/20 0.37
GMNN O75496 1/20 0.37
LMNA P02545 1/20 0.37
TP53 P04637 1/20 0.37
CYP1A2 P05177 1/20 0.37
POLB P06746 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10821869 0.84 PTPN1 (0.52) CDC25ACDC25BPTPN1IDO1PTGS2
SCHEMBL2072765 0.78 CDC25A (0.38) CDC25ACDC25BPTPN1IDO1PTGS2
SCHEMBL14409055 0.75 CDC25A (0.58) CDC25ACDC25BPTPN1IDO1PTGS2
SCHEMBL5916035 0.72 PTPN1 (0.46) CDC25ACDC25BPTPN1IDO1PTGS2
SCHEMBL217595 0.71 GPR84 (0.33) CDC25ACDC25BGPR84
SCHEMBL9124914 0.69 GPR84 (0.41) CDC25ACDC25BPTPN1ALDH1A1GPR84
SCHEMBL5916036 0.68 PTPN1 (0.42) CDC25ACDC25BPTPN1IDO1PTGS2
SCHEMBL1572195 0.68 MAPT (0.43) CDC25ACDC25BPTPN1IDO1KDM4E
SCHEMBL29926234 0.68 MAPT (0.43) CDC25ACDC25BPTPN1IDO1KDM4E
SCHEMBL7038230 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0795564-B1 Process for hydrogenation of conjugated diene polymers and catalyst compositions suitable for use therein SHELL INT RESEARCH (NL) 2001-01-10 EP claimed
US-5925717-A SELECTIVE HYDROGENATION OF POLYMERS WITH TITANIUM CATALYSTS WITH INDENE COMPOUND LIGANDS SHELL OIL COMPANY (US) 1999-07-20 US claimed
EP-0795564-A1 Process for hydrogenation of conjugated diene polymers and catalyst compositions suitable for use therein SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1997-09-17 EP claimed
EP-0795564-B1 Process for hydrogenation of conjugated diene polymers and catalyst compositions suitable for use therein SHELL INT RESEARCH (NL) 2001-01-10 EP disclosed
US-5925717-A SELECTIVE HYDROGENATION OF POLYMERS WITH TITANIUM CATALYSTS WITH INDENE COMPOUND LIGANDS SHELL OIL COMPANY (US) 1999-07-20 US disclosed
EP-0795564-A1 Process for hydrogenation of conjugated diene polymers and catalyst compositions suitable for use therein SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1997-09-17 EP disclosed