SCHEMBL7815432

SCHEMBL7815432

CCCCCCOc1cccc2c1C(OCC)(OCC)NC2=N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE5A O76074 3/20 0.38
PDE4A P27815 2/20 0.38
PDE4B Q07343 2/20 0.38
PDE4C Q08493 2/20 0.38
PDE4D Q08499 2/20 0.38
MCHR1 Q99705 2/20 0.38
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
LMNA P02545 2/20 0.37
NR1I2 O75469 1/20 0.37
CHRM2 P08172 1/20 0.37
CYP3A4 P08684 1/20 0.37
ADRA2A P08913 1/20 0.37
MAPT P10636 1/20 0.37
OPRK1 P41145 1/20 0.37
HTR2B P41595 1/20 0.37
SLC6A3 Q01959 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.35
PTPN11 Q06124 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7825435 1.00 PDE5A (0.38) PDE5APDE4APDE4BPDE4CPDE4D
SCHEMBL7826687 0.95 CYP1A2 (0.39) PDE5APDE4APDE4BPDE4CPDE4D
SCHEMBL7826155 0.91 PDE5A (0.34) PDE5APDE4APDE4BPDE4CPDE4D
SCHEMBL7827943 0.88 PDE5A (0.39) PDE5APDE4APDE4BPDE4CPDE4D
SCHEMBL7826408 0.88 PDE5A (0.39) PDE5APDE4APDE4BPDE4CPDE4D
SCHEMBL7828017 0.88 PDK2 (0.37) PDE5AMAPTL3MBTL1KDM4ENPSR1
SCHEMBL7823190 0.83 CYP1A2 (0.40) PDE5APDE4APDE4BPDE4CPDE4D
SCHEMBL7827899 0.81 PRKCA (0.40) PDE5APDE4APDE4BPDE4CPDE4D
SCHEMBL7828606 0.81 PRKCA (0.40) PDE5APDE4APDE4BPDE4CPDE4D
SCHEMBL7816569 0.81 GAA (0.33) KMT2ALMNAMAPTSMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0679640-B1 Carboxylate and heat-sensitive recording material using same MITSUI CHEMICALS INC (JP) 2001-08-08 EP disclosed
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed