Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL986067 | 0.84 | KMT2A (0.48) | KMT2ACYP2D6ALDH1A1LMNACYP3A4 | |
| SCHEMBL286685 | 0.84 | KMT2A (0.48) | KMT2ACYP2D6ALDH1A1LMNACYP3A4 | |
| SCHEMBL6372424 | 0.83 | ALDH1A1 (0.54) | KMT2ACYP2D6ALDH1A1CYP3A4TSHR | |
| SCHEMBL6176608 | 0.82 | KMT2A (0.47) | KMT2ACYP2D6ALDH1A1LMNACYP3A4 | |
| SCHEMBL10827238 | 0.82 | KMT2A (0.47) | KMT2ACYP2D6ALDH1A1LMNACYP3A4 | |
| SCHEMBL1030015 | 0.82 | ALDH1A1 (0.53) | KMT2ACYP2D6ALDH1A1LMNACYP3A4 | |
| SCHEMBL11386291 | 0.81 | KMT2A (0.47) | KMT2ACYP2D6ALDH1A1LMNACYP3A4 | |
| SCHEMBL113808 | 0.81 | CYP2D6 (0.46) | KMT2ACYP2D6ALDH1A1LMNACYP3A4 | |
| SCHEMBL28881766 | 0.79 | ALDH1A1 (0.50) | KMT2ACYP2D6ALDH1A1CYP3A4TSHR | |
| SCHEMBL6372481 | 0.79 | KMT2A (0.41) | KMT2ACYP2D6ALDH1A1CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1092649-C | Thiazolidinone compound or angina pectoris therapeutic or prophylactic agent containing the same as active ingredient | SANKYO CO (JP) | 2002-10-16 | — | — | CN | disclosed |
| EP-0798298-B1 | THIAZOLIDINONE OR OXAZOLIDINONE DERIVATIVES TO TREAT ANGINA PECTORIS OR COMPOSITIONS CONTAINING THE SAME AS ACTIVE INGREDIENT | SANKYO CO (JP) | 2001-08-08 | — | — | EP | disclosed |
| US-5843973-A | Thiazolidinone compounds and composition for angina pectoris comprising the compounds as an active ingredient | SANKYO COMPANY, LIMITED (JP) | 1998-12-01 | — | — | US | disclosed |
| CN-1175250-A | Thiazolidinone compound or angina pectoris therapeutic or prophylactic agent containing the same as active ingredient | SANKYO CO (JP) | 1998-03-04 | — | — | CN | disclosed |
| EP-0798298-A1 | THIAZOLIDINONE COMPOUNDS OR ANGINA PECTORIS REMEDY OR PREVENTIVE CONTAINING THE SAME AS ACTIVE INGREDIENT | SANKYO COMPANY LIMITED (JP) | 1997-10-01 | — | — | EP | disclosed |
| EP-0346756-A1 | Process for production of sulfonium compounds | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1989-12-20 | — | — | EP | disclosed |