Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 16/20 | 0.70 |
| ▸ | BRD4 | O60885 | 10/20 | 0.68 |
| ▸ | BRDT | Q58F21 | 4/20 | 0.68 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7815820 | 0.88 | MAPK14 (0.91) | MAPK14BRD4BRDTMAPK11 | |
| SCHEMBL6943872 | 0.83 | MAPK14 (1.00) | MAPK14BRD4BRDTMAPK11 | |
| SCHEMBL6943923 | 0.81 | MAPK14 (1.00) | MAPK14BRD4BRDT | |
| SCHEMBL22730499 | 0.80 | MAPK14 (1.00) | MAPK14BRD4BRDT | |
| SCHEMBL3300552 | 0.78 | MAPK14 (1.00) | MAPK14BRD4BRDTMAPK11 | |
| Trifluoroacetic Acid SCHEMBL6948788 | 0.77 | MAPK14 (0.87) | MAPK14BRD4BRDTMAPK11 | |
| SCHEMBL22730374 | 0.76 | MAPK14 (0.88) | MAPK14BRD4BRDT | |
| SCHEMBL8655733 | 0.75 | MAPK14 (0.66) | MAPK14BRD4BRDTMAPK11 | |
| Trifluoroacetic Acid SCHEMBL6950915 | 0.75 | MAPK14 (0.86) | MAPK14BRD4BRDT | |
| SCHEMBL6943778 | 0.75 | MAPK14 (1.00) | MAPK14BRD4BRDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996446-A4 | NOVEL SUBSTITUTED IMIDAZOLE COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2001-08-29 | — | — | EP | claimed |
| EP-0996446-A1 | NOVEL SUBSTITUTED IMIDAZOLE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-03 | — | — | EP | claimed |
| WO-1999001131-A1 | NOVEL SUBSTITUTED IMIDAZOLE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-01-14 | — | — | WO | claimed |