Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD5 | P21918 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.30 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.30 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7813110 | 1.00 | ESR1 (0.34) | ESR1DRD2DRD1DRD4DRD5 | |
| SCHEMBL7819405 | 0.98 | ESR1 (0.34) | ESR1DRD2DRD1DRD4DRD5 | |
| SCHEMBL7816101 | 0.92 | ESR1 (0.37) | ESR1DRD2DRD1DRD4DRD5 | |
| SCHEMBL7819408 | 0.92 | ESR1 (0.37) | ESR1DRD2DRD1DRD4DRD5 | |
| SCHEMBL7813295 | 0.85 | ESR1 (0.34) | ESR1 | |
| SCHEMBL7813618 | 0.85 | ESR1 (0.34) | ESR1 | |
| SCHEMBL7805977 | 0.83 | ESR1 (0.34) | ESR1 | |
| SCHEMBL7813636 | 0.81 | DRD2 (0.33) | ESR1DRD2DRD1DRD4DRD5 | |
| SCHEMBL7805794 | 0.81 | DRD2 (0.33) | ESR1DRD2DRD1DRD4DRD5 | |
| SCHEMBL7263507 | 0.81 | ESR1 (0.36) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087959-A1 | NOVEL BENZOPYRAN OR THIOBENZOPYRAN DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-04-04 | — | — | EP | claimed |
| WO-1999065893-A1 | NOVEL BENZOPYRAN OR THIOBENZOPYRAN DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 1999-12-23 | — | — | WO | claimed |