Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.30 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7815067 | 0.81 | HSD17B10 (0.33) | KDM4EHSD17B10HPGDMAPTHTT | |
| SCHEMBL7671509 | 0.76 | KDM4E (0.38) | KDM4EHSD17B10HPGDMAPTSMN1; SMN2 | |
| SCHEMBL7619023 | 0.70 | CYP1A2 (0.34) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL7624166 | 0.69 | RYR2 (0.30) | RYR2 | |
| SCHEMBL984617 | 0.69 | NCEH1 (0.46) | KDM4EHSD17B10HPGDMAPTHTT | |
| SCHEMBL8602345 | 0.66 | KDM4E (0.40) | KDM4EHSD17B10HPGDMAPTHTT | |
| SCHEMBL1598718 | 0.64 | POLB (0.54) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL7474688 | 0.63 | KDM4E (0.35) | KDM4EHSD17B10ALDH1A1RYR2 | |
| SCHEMBL6970278 | 0.63 | KDM4E (0.37) | KDM4EHSD17B10HPGDMAPTHTT | |
| SCHEMBL8604736 | 0.63 | KDM4E (0.40) | KDM4EHSD17B10HPGDMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135385-A1 | THIOCHROMANOYLPYRAZOLONE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-26 | — | — | EP | disclosed |
| WO-2000034270-A1 | THIOCHROMANOYLPYRAZOLONE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-15 | — | — | WO | disclosed |