Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7815909 | 0.81 | KDM4E (0.36) | HSD17B10KDM4EHPGDALDH1A1MAPT | |
| SCHEMBL7786756 | 0.79 | PPARG (0.31) | HSD17B10KDM4EHPGD | |
| SCHEMBL7670644 | 0.78 | ALDH1A1 (0.36) | HSD17B10KDM4EHPGDALDH1A1MAPT | |
| SCHEMBL13725344 | 0.63 | HSD17B10 (0.42) | HSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL1841425 | 0.61 | KDM4E (0.42) | HSD17B10KDM4EHPGDALDH1A1MAPT | |
| SCHEMBL18182129 | 0.61 | HPGD (0.54) | HSD17B10KDM4EHPGDALDH1A1HTT | |
| SCHEMBL6950322 | 0.58 | KDM4E (0.46) | HSD17B10KDM4EHPGDALDH1A1MAPT | |
| SCHEMBL1839261 | 0.58 | NCEH1 (0.46) | HSD17B10KDM4EHPGDALDH1A1MAPT | |
| SCHEMBL5201253 | 0.58 | CUL4A (0.40) | HSD17B10KDM4EHPGDALDH1A1MAPT | |
| SCHEMBL11925422 | 0.58 | KDM4E (0.70) | HSD17B10KDM4EHPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135385-A1 | THIOCHROMANOYLPYRAZOLONE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-26 | — | — | EP | disclosed |
| WO-2000034270-A1 | THIOCHROMANOYLPYRAZOLONE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-15 | — | — | WO | disclosed |