Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.41 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32688983 | 0.85 | POLB (0.51) | POLBHSD11B1HPGDNPC1RAB9A | |
| SCHEMBL21896029 | 0.84 | POLB (0.50) | POLBHSD11B1HPGDNPC1RAB9A | |
| SCHEMBL32688847 | 0.80 | POLB (0.55) | POLBHSD11B1HPGDNPC1RAB9A | |
| SCHEMBL32689185 | 0.80 | POLB (0.55) | POLBHSD11B1HPGDNPC1RAB9A | |
| SCHEMBL8544460 | 0.79 | POLB (0.58) | POLBHSD11B1HPGDNPC1RAB9A | |
| SCHEMBL32688645 | 0.79 | POLB (0.49) | POLBHSD11B1HPGDNPC1RAB9A | |
| SCHEMBL5400134 | 0.78 | POLB (0.47) | POLBHSD11B1HPGDNPC1RAB9A | |
| SCHEMBL32689110 | 0.78 | POLB (0.49) | POLBHSD11B1HPGDNPC1RAB9A | |
| SCHEMBL12953539 | 0.77 | EPHX2 (0.54) | POLBHSD11B1HPGDNPC1RAB9A | |
| SCHEMBL32688896 | 0.77 | POLB (0.47) | POLBHSD11B1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080089-A1 | PYRAZOLYLDIOXOTHIOCHROMANOYL DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-07 | — | — | EP | claimed |
| WO-1999059991-A1 | PYRAZOLYLDIOXOTHIOCHROMANOYL DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-25 | — | — | WO | claimed |